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What is Comfortis?

Comfortis is the first FDA-approved, chewable tablet that kills fleas and prevents flea infestations on dogs for a full month. Only Comfortis offers you all of these benefits in a single product: Starts killing fleas within 30 minutes. Lasts a full month. Kills fleas before they can lay eggs. The convenience of a chewable, synthetic beef-flavored tablet. Spinosad, the active ingredient in Comfortis, is environmentally friendly.

Manufacturer: Elanco Animal Health

For: Dogs (14 weeks of age or older)

Benefits:
* Starts killing fleas within 30 minutes
* Lasts a full month
* Kills fleas before they can lay eggs
* Comes in a convenient chewable, beef-flavored tablet
* Spinosad, the active ingredient in Comfortis, is environmentally friendly

How it works:

Spinosad kills fleas by causing excitation of the insect's nervous system, leading to paralysis and rapid death.

Cautions:

Side effects may occur, including vomiting. If your pet is experiencing loss of appetite, lethargy, or any other difference in behavior, contact your veterinarian. The FDA has received reports of adverse reactions in dogs receiving the drug Comfortis (spinosad) concurrently with high, extra-label doses of ivermectin. Dogs receiving extra-label doses of ivermectin to treat non-responsive demodectic mange and other conditions have developed signs of ivermectin toxicity.

More Information:

Brand Name: Comfortis (Lilly)

Generic Name: Spinosad

What is Comfortis: Comfortis is a chewable, synthetic beef flavored tablet (derived from pork protein and hydrolyzed soy) that is given to the dog to kill fleas and prevent flea infestations for one month. Comfortis chewable tablets are for monthly use in dogs and puppies 14 weeks of age and older.

What should I discuss with my veterinarian before giving Comfortis to my pet: Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).

How should this medication be given: Give Comfortis chewable tablets with food. Give Comfortis chewable tablets once a month. Comfortis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Comfortis at room temperature (68-77??)

What happens if I miss a dose: Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.

What happens if I overdose the pet: Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.

What should I avoid while giving Comfortis: Your pet may maintain normal activities and interactions while being given Comfortis. The safe use of Comfortis chewable tablets in male dogs intended for breeding has not been established.

What are the possible side effects of Comfortis: Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Comfortis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.

What other drugs will affect Comfortis: Talk to your veterinarian before giving any prescription or over the counter medications.

Where can I get more information: Your pharmacist has additional information about Comfortis written for health professionals that you may read.

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